Formestane
CAS:566-48-3
Molecular formula:C19H26O3
Molecular weight:302.408 g/mol
Formestane is a medicine that is known as an aromastase inhibitor and it prevents the production of the female hormone called oestrogen.Formestane (4-hydroxyandrostenedione) is a new mechanism based aromatase inhibitor which irreversibly inactivates the enzyme, preventing the conversion of androstenedione to oestradiol and oestrone. Formestane is a powerful suicide aromatase inhibitor. It also decreases the receptor counts for both estrogen and progesterone.Formestane is now approved in Europe for the treatment of metastatic breast cancer in women who have failed tamoxifen therapy.
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