The Introduction of Clindamycin hydrochloride
Clindamycin hydrochloride is antibiotics. Is a derivative of lincomycin, listed since 1970 in China. Antibacterial spectrum and lincomycin same, but the strong antibacterial effect, mainly used in clinical osteomyelitis caused by anaerobic bacteria infections, respiratory infections, biliary tract infections, endocarditis, otitis media, skin and soft tissue infections and septicemia. In the application of the most common adverse reactions: allergic reactions, injection of local irritation and liver function abnormalities, the most serious is pseudomembranous colitis (PMC).
Fusobacterium genus, Actinomyces, Peptococcus, Peptostreptococcus, etc. Most are sensitive to the chemicals. This product acts on the 50S ribosomal subunit of susceptible ones, to prevent the extension of the peptide chain, thereby inhibiting bacterial protein synthesis in cells, the general line antimicrobial agents, but at high concentrations, certain bacteria also has a bactericidal effect. This product acts on the 50S ribosomal subunit of susceptible ones, to prevent the extension of the peptide chain, thereby inhibiting bacterial protein synthesis in cells, the general line antimicrobial agents, but at high concentrations, certain bacteria also has a bactericidal effect.
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