Celastrol
Molecular Formula:C29H38O4
CAS No.: 34157-83-0
About Celastrol:
Celastrol is a potent anti-inflammatory that is extracted from the root bark of an ivy-like vine in China. Celastrol was used for years as a natural remedy for inflammatory conditions. Several pharmaceutical companies are studying its multiple properties and have found it to be quite intensely immunosuppressive as well as anti-inflammatory. Celastrol inhibits macrophage activation, MHC I and II processing, TNF-alpha, IL1, IL2, and IL6.
Celastrol, a Triterpene Extracted from the Chinese "Thunder of God Vine," Is a Potent Proteasome Inhibitor and Suppresses Human Prostate Cancer Growth in Nude Mice.
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