FDA approval of abacavir was accepted in 1998 for developed and pediatric use in aggregate anti-HIV therapy. Approval was based on studies assuming bigger CD4 T-lymphocyte counts and HIV viral endless on a 3-drug dieting of zidovudine, lamivudine, and abacavir, compared with the 2-drug dieting of zidovudine and lamivudine.Abacavir is accessible in book and articulate band-aid formulations. It is accustomed for twice-daily or once-daily dosing. Abacavir is aswell accessible in aggregate with lamivudine as a alone book for once-daily dosing (Epzicom, Kivexa), and in aggregate with lamivudine and zidovudine as a alone book for twice-daily dosing (Trizivir).It is a nucleoside analog about-face transcriptase inhibitor (NRTI) acclimated to amusement HIV and AIDS. It is accessible beneath the barter name Ziagen (ViiV Healthcare) and in the aggregate formulations Trizivir (abacavir, zidovudine and lamivudine) and Kivexa/Epzicom(abacavir and lamivudine) . It has been able-bodied tolerated: the capital ancillary aftereffect is hypersensitivity, which can be severe, and in attenuate cases, fatal. Genetic testing can announce whether an alone will be hypersensitive; over 90% of patients can cautiously yield abacavir. However, in a abstracted study, the accident of affection advance added by about 90%.Abacavir tablets and articulate solution, in aggregate with added antiretroviral agents, are adumbrated for the analysis of HIV-1 infection.
Abacavir should consistently be acclimated in aggregate with added antiretroviral agents. Abacavir should not be added as a alone abettor if antiretroviral regimens are afflicted due to accident of virologic response.Abacavir was accustomed in 1998 as an antiretroviral biologic (ARV) for humans with HIV infection. It has been advised in adults and accouchement 3 months old and older. There are no complete rules about if to alpha ART. You and your bloom affliction provider should accede your CD4 corpuscle count, your viral load, any affection you are having, and your attitude about demography ART. Fact Sheet 404 has added advice about guidelines for the use of ART.