Docetaxel (as all-embracing or below the bargain name Taxotere) is a clinically complete anti-mitotic chemotherapy medication (that is, it interferes with corpuscle division). It is acclimated mainly for the assay of breast, ovarian, prostate, and non-small corpuscle lung cancer. Docetaxel has an FDA acclimatized affirmation for assay of patients who acquire locally advanced, or metastatic breast or non small-cell lung bane who acquire undergone anthracycline-based chemotherapy and bootless to stop bane progression or relapsed and a European approval for use in hormone-refractory prostate cancer.
According to a 2005 article in the annual Drugs, docetaxel administered as a one-hour cooler every three weeks about over a ten aeon course, docetaxel is brash as or added able than doxorubicin, paclitaxel and fluorouracil as a cytotoxic antimicrotubule agent. However the adequacy of Docetaxel vs. Paclitaxel and added taxenes is still controversial. Several added abreast online autograph acquire activate "no affirmation that regimens complete docetaxel crop greater allowances than those including paclitaxel." Additionally, the optimal scheduling of docetaxel and added taxenes charcoal unconfirmed. A three-week administering calendar acclimated to be and is still brash able but new studies are advertence a annual calendar adeptness be better. A 2010 article in Current Clinical Pharmacology states, "weekly administering has emerged as the optimal schedule." Docetaxel is marketed accepted below the name Taxotere by Sanofi-Aventis. Annual sales in 2010 were Euro 2.122 billion ($US 3.1 billion). The credible comatose in 2010.
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