The use of trimethoprim

trimethoprim preferred as an antimicrobial agent, a prokaryotic enzyme selective inhibitors of dihydrofolate reductase; specific formulations inhibitor, is widely used to study the dihydrofolate reductase; by a particular prokaryotic dihydrofolate reductase (DHFR) inhibition of four hydrogen folic acid synthesis. Antibacterial agent. The antibacterial range and close to the sulfa drug. Enhance its efficacy when used in conjunction with the sulfa drugs, several times to ten times. Respiratory tract infections, senile chronic bronchitis, dysentery, urinary tract infections, enteritis, typhoid, malaria embolism. trimethoprim used as feed additives, and sulfa drugs and anti-biological and obvious synergies, increase the effect of 10 to several times. trimethoprim not be used alone, generally use a 1:5 ratio, and treat livestock E. coli-induced sepsis, pullorum disease, fowl typhoid, cholera, respiratory system of secondary bacterial infection. Can also be used for the prevention and treatment of coccidiosis.
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